6 September 2008 : Serie A Transfers Updated| Player | Position | From | To | Fee €m | |
| Cerci | MF | Roma | Atalanta | Loan | |
| Cigarini | MF | Parma | Atalanta | 5.00 | |
| Garics | DF | Napoli | Atalanta | c/o | |
| Vieri | FW | Fiorentina | Atalanta | Free | |
| Britos | DF | Montevideo Wanderers | Bologna | 4.00 | |
| Campironi | GK | Milan | Bologna | u/d | |
| Coda | FW | Treviso | Bologna | c/o | |
| Coelho | DF | Corinthians | Bologna | Loan | |
| Di Vaio | FW | Genoa | Bologna | u/d | |
| Marchini | MF | Triestina | Bologna | u/d | |
| Mudingayi | MF | Lazio | Bologna | 6.00 | |
| Okaka | FW | Roma | Bologna | u/d | |
| Rodriguez | DF | Penarol | Bologna | Loan | |
| Zenoni | DF | Sampdoria | Bologna | u/d | |
| Smolarek | FW | Santander | Bolton | Loan | |
| Agostini | DF | Contract Extension | Cagliari | 2011 | |
| Allegri | Coach | Out of contract | Cagliari | n/a | |
| Aquafresca | FW | Inter | Cagliari | Loan | |
| Conti | MF | Contract Extension | Cagliari | 2011 | |
| Lazzari | MF | Atalanta | Cagliari | c/o | |
| Magliocchetti | DF | Roma | Cagliari | c/o | |
| Marchetti | GK | Albinoleffe | Cagliari | u/d | |
| Matheu | DF | Independiente | Cagliari | u/d | |
| Matri | FW | Milan | Cagliari | u/d | |
| Catellani | FW | Reggina | Catania | c/o | |
| Di Cosmo | FW | Igea Virtus | Catania | u/d | |
| Dica | MF | Steaua Bucharest | Catania | 2.00 | |
| Kosicky | GK | Inter Bratislava | Catania | u/d | |
| Ledesma | MF | Boca Junior | Catania | u/d | |
| Paolucci | FW | Juventus | Catania | Loan | |
| D'Aguanno | MF | Trapani | Chievo | u/d | |
| D'Anna | MF | Pisa | Chievo | u/d | |
| Granoche | FW | Triestina | Chievo | u/d | |
| Grippo | MF | Bellinzona | Chievo | u/d | |
| Kerlon | FW | Cruzeiro | Chievo | u/d | |
| Langella | FW | Udinese | Chievo | Loan | |
| Morero | DF | Udinese | Chievo | u/d | |
| Patrascu | MF | Piacenza | Chievo | Loan | |
| Pellissier | FW | Contract Extension | Chievo | 2013 | |
| Pizzi | MF | Udinese | Chievo | Loan | |
| Sorrentino | GK | AEK Athens | Chievo | Free | |
| Almiron | MF | Juventus | Fiorentina | Loan | |
| Comotto | DF | Torino | Fiorentina | u/d | |
| Frey | GK | Contract Extension | Fiorentina | 2013 | |
| Gilardino | FW | Milan | Fiorentina | 15.00 | |
| Jefferson | FW | Parana | Fiorentina | u/d | |
| Jovetic | FW | Partizan Belgrade | Fiorentina | 8.00 | |
| Melo | MF | Almeria | Fiorentina | 13.00 | |
| Mutu | FW | Contract Extension | Fiorentina | 2012 | |
| Storari | GK | Milan | Fiorentina | Loan | |
| Vargas | DF | Catania | Fiorentina | 12.00 | |
| Zauri | DF | Lazio | Fiorentina | Loan | |
| Biava | DF | Palermo | Genoa | u/d | |
| Bocchetti | DF | Frosinone | Genoa | u/d | |
| Di Gennaro | MF | Milan | Genoa | Loan | |
| Ferrari | DF | Roma | Genoa | Free | |
| Gasbarroni | MF | Parma | Genoa | u/d | |
| Mesto | DF | Reggina | Genoa | 3.00 | |
| Milito | FW | Zaragoza | Genoa | u/d | |
| Natalino | DF | Crotone | Genoa | u/d | |
| Palladino | FW | Juventus | Genoa | Loan | |
| Papastathopoulos | DF | AEK | Genoa | u/d | |
| Paro | MF | Juventus | Genoa | 2.00 | |
| Pinau | DF | Monaco | Genoa | u/d | |
| Potenza | DF | Fiorentina | Genoa | u/d | |
| Rossi | MF | Contract Extension | Genoa | 2011 | |
| Balotelli | FW | Contract Extension | Inter | 2011 | |
| Cordoba | DF | Contract Extension | Inter | 2012 | |
| Coutinho | MF | Vasco da Gama | Inter | 3.80 | |
| Mancini | MF | Roma | Inter | 12.50 | |
| Mourinho | Coach | Out of contract | Inter | n/a | |
| Muntari | MF | Portsmouth | Inter | 16.00 | |
| Orlandoni | GK | Contract Extension | Inter | 2009 | |
| Quarsema | MF | Porto | Inter | 18.60 | |
| Samuel | DF | Contract Extension | Inter | 2012 | |
| Amauri | FW | Palermo | Juventus | 15.30 | |
| Chiellini | DF | Contract Extension | Juventus | 2013 | |
| Ekdal | MF | Brommapojkarna | Juventus | 0.60 | |
| Knezevic | DF | Livorno | Juventus | u/d | |
| Manninger | GK | Udinese | Juventus | 1.00 | |
| Mellberg | DF | Aston Villa | Juventus | Free | |
| Nedved | MF | Contract Extension | Juventus | 2009 | |
| Poulsen | MF | Sevilla | Juventus | 10.00 | |
| Amoruso | FW | Reggina | Lazio | u/d | |
| Carrizo | GK | River Plate | Lazio | 7.00 | |
| Matuzalem | MF | Zaragoza | Lazio | Loan | |
| Moti | DF | Dinamo Bucharesti | Lazio | u/d | |
| Radu | DF | Dinamo Bucharesti | Lazio | u/d | |
| Rozenhal | DF | Newcastle | Lazio | 3.90 | |
| Zarate | MF | Al-Sadd | Lazio | Loan | |
| Antunes | DF | Roma | Lecce | u/d | |
| Beretta | Coach | Out of contract | Lecce | n/a | |
| Cacia | FW | Fiorentina | Lecce | u/d | |
| Castillo | FW | Pisa | Lecce | u/d | |
| Fabiano | DF | Monza | Lecce | u/d | |
| Leonardo | FW | Internacional | Lecce | Loan | |
| Abate | MF | Empoli | Milan | u/d | |
| Borriello | FW | Genoa | Milan | 10.00 | |
| Cardaccio | MF | Nacional | Milan | Loan | |
| Felipe | GK | Santos | Milan | u/d | |
| Flamini | MF | Arsenal | Milan | Free | |
| Maldini | DF | Contract Extension | Milan | 2009 | |
| Ronaldinho | MF | Barcelona | Milan | 21.00 | |
| Senderos | DF | Arsenal | Milan | Loan | |
| Shevchenko | FW | Chelsea | Milan | u/d | |
| Viudez | MF | Defensor | Milan | u/d | |
| Zambrotta | MF | Barcelona | Milan | 9.00 | |
| Aronica | DF | Reggina | Napoli | 2.70 | |
| Blasi | MF | Juventus | Napoli | u/d | |
| Denis | FW | Independiente | Napoli | 7.60 | |
| Maggio | MF | Sampdoria | Napoli | 8.00 | |
| Russotto | MF | Bellinzona | Napoli | u/d | |
| Amelia | GK | Livorno | Palermo | 6.00 | |
| Bovo | DF | Genoa | Palermo | u/d | |
| Budan | FW | Parma | Palermo | u/d | |
| Carrozzieri | DF | Atalanta | Palermo | u/d | |
| Kjaer | DF | Midtylland | Palermo | u/d | |
| Lanzafame | FW | Juventus | Palermo | c/o | |
| Liverani | MF | Fiorentina | Palermo | Free | |
| Mchedlidze | FW | Empoli | Palermo | Loan | |
| Nocerino | MF | Juventus | Palermo | Free 1 | |
| Pisano | DF | Torino | Palermo | u/d | |
| Raggi | DF | Empoli | Palermo | u/d | |
| Succi | FW | Ravenna | Palermo | c/o | |
| Aubey | DF | Lens | Reggina | u/d | |
| Brienza | MF | Palermo | Reggina | Loan | |
| Corradi | FW | Manchester City | Reggina | u/d | |
| Costa | DF | Bologna | Reggina | u/d | |
| Di Gennaro | MF | Genoa | Reggina | u/d | |
| Fabiano | DF | Genoa | Reggina | Loan | |
| Flores | FW | Udinese | Reggina | Loan | |
| Mangane | MF | Lens | Reggina | u/d | |
| Mesto | DF | Udinese | Reggina | u/d | |
| Paloschi | FW | Milan | Reggina | Loan | |
| Rakic | FW | Strasbourg | Reggina | u/d | |
| Santos | DF | Genoa | Reggina | Free | |
| Sestu | MF | Avellino | Reggina | Loan | |
| Tello | MF | O'Higgins | Reggina | 1.00 | |
| Zahorski | FW | Concordia | Reggina | Loan | |
| Andreolli | DF | Inter | Roma | u/d | |
| Baptista | FW | Real Madrid | Roma | 9.00 | |
| Brighi | MF | Contract Extension | Roma | 2012 | |
| De Rossi | MF | Contract Extension | Roma | 2012 | |
| Esposito | FW | Cagliari | Roma | u/d | |
| Loria | DF | Siena | Roma | u/d | |
| Menez | MF | Monaco | Roma | 12.00 | |
| Ribeiro | MF | Fiorentina | Roma | u/d | |
| Vucinic | FW | Lecce | Roma | 12.00 | |
| Accardi | DF | Contract Extension | Sampdoria | 2012 | |
| Bottinelli | DF | San Lorenzo | Sampdoria | u/d | |
| Cassano | FW | Real Madrid | Sampdoria | 7.00 | |
| Dessena | MF | Parma | Sampdoria | c/o | |
| Fornaroli | FW | Nacional | Sampdoria | 3.00 | |
| Kondrasen | MF | Bodo Glimt | Sampdoria | u/d | |
| Mazzari | Coach | Contract Extension | Sampdoria | 2010 | |
| Padalino | MF | Piacenza | Sampdoria | u/d | |
| Pieri | DF | Contract Extension | Sampdoria | 2010 | |
| Sammarco | MF | Milan | Sampdoria | 2.40 | |
| Stankevicius | DF | Brescia | Sampdoria | u/d | |
| Arthur | GK | Roma | Siena | u/d | |
| Barusso | MF | Roma | Siena | Loan | |
| Belmonte | DF | Bari | Siena | u/d | |
| Curci | GK | Roma | Siena | Loan | |
| Del Prete | DF | Juventus | Siena | Loan | |
| Galloppa | MF | Roma | Siena | u/d | |
| Kharja | MF | Piacenza | Siena | u/d | |
| Larrondo | FW | Atletico Progeso | Siena | Loan | |
| Rossettini | DF | Padova | Siena | u/d | |
| Vergassola | MF | Contract Extension | Siena | 2011 | |
| Zuniga | DF | Nacional | Siena | u/d | |
| Abate | MF | Milan | Torino | Loan | |
| Abbruscato | FW | Lecce | Torino | c/o | |
| Amoruso | FW | Reggina | Torino | u/d | |
| Bianchi | FW | Manchester City | Torino | 9.00 | |
| Bjelanovic | FW | Ascoli | Torino | c/o | |
| Calderoni | GK | Treviso | Torino | u/d | |
| Fontana | GK | Contract Extension | Torino | 2009 | |
| Moro | FW | Messina | Torino | c/o | |
| Pratali | DF | Empoli | Torino | 3.00 | |
| Saumel | MF | Sturm Graz | Torino | u/d | |
| Basta | MF | Red Star Blegrade | Udinese | u/d | |
| Belardi | GK | Juventus | Udinese | u/d | |
| Corvette | MF | Audax Italiano | Udinese | u/d | |
| Di Natale | FW | Contract Extension | Udinese | 2013 | |
| Domizzi | DF | Napoli | Udinese | u/d | |
| Floro Flores | FW | Arezzo | Udinese | u/d | |
| Inler | MF | Contract Extension | Udinese | 2013 | |
| Langella | FW | Atalanta | Udinese | u/d | |
| Nef | DF | Piacenza | Udinese | u/d | |
| Vuyadinovich | DF | CSKA Moscow | Udinese | u/d | |
| 281.40 | |||||
| u/d = undisclosed | |||||
| c/o = co-ownership | |||||
| 1 = Nocerino joins Palermo as part of Amauri's transfer to Juventus | |||||